Intermediates for preparing enantiomerically pure imidazo[4,5,1-

Details Intermediates for preparing enantiomerically pure imidazo[4,5,1- Intermediates for preparing enantiomerically pure imidazo[4,5,1-

1995-03-30

1996-08-06

Burn, Brian M.

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

564 92, 564220, 564 97, 564 99, C07C31103

Patent

active

055435700

ABSTRACT:
Process for preparing enantiomerically pure imidazo[4,5,1 -jk][1,4]benzodiazepin -2(1H)-thiones of formula ##STR1## starting from 2,6-dihalo-3-nitrobenzyl derivatives (II) and suitably N-protected 1,2-diaminopropanes (III) ##STR2## Novel enantiomerically pure intermediates of formula (III) and (IV) are prepared in the course of the present process.

REFERENCES:
patent: 4665227 (1987-05-01), Coldtsky et al.
patent: 4720580 (1988-01-01), Buzby, Jr.
patent: 5292756 (1994-03-01), Duggan et al.

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