Intermediates for preparing .alpha.-carboxy-.alpha.-(3-thienyl)p

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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2602391, 544 26, 544 27, 544 22, 544 30, 544 16, C07D33324

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active

040666646

ABSTRACT:
A new process is disclosed for the preparation of alpha-carboxy-alpha-phenyl(or 3-thienyl)penicillin and cephalosporin derivatives.
The process comprises reacting a 1.3-dioxane-4.6-dione derivative with the desired penicillanic or cephalosporanic acid derivative.

REFERENCES:
scheuer, J. Amer. Chem. Soc. 80: 4933-4938, (1958).
Burger, "Medicinal Chemistry" pp. 72-81, (1960).
Alles et al., J. Pharm. & Expt. Therap., 72: 265, (1941).

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