Intermediates for preparing 3,4-diamino-1,2,5-thiadiazoles

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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544 60, 544 59, 544360, 544398, 544402, 544124, 544133, 544146, 544379, 544152, 548566, 548569, 548135, 546187, 546194, 546246, 546255, 546268, 546209, 546256, 546283, 546332, 546212, 260239B, 260239BA, 564243, 549 59, 549491, C07D29514, C07D21106, C07D40112

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045173664

ABSTRACT:
Histamine H.sub.2 -receptor antagonists of the formula ##STR1## wherein A, m, Z, n and R.sup.1 are as defined herein, and their nontoxic pharmaceutically acceptable salts, hydrates and solvates are novel anti-ulcer agents which are prepared by ring closure of a substituted ethanediimidamide of the formula ##STR2##

REFERENCES:
patent: 4374248 (1983-02-01), Crenshaw et al.
Komin et al., "J. Het. Chem", vol. 13, pp. 13-22 (1976).
Weinstock et al., "Advances in Heterocyclic Chemistry", vol. 9, Academic Press, New York (1978), pp. 107-163.
Weinstock et al., "J. Org. Chem.", vol. 32, pp. 2823-2839 (1967).
Komin et al., "J. Org. Chem.", vol. 40, pp. 2749-2752 (1975).

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