Intermediates for inhibitors of HIV protease and method of prepa

Details Intermediates for inhibitors of HIV protease and method of prepa Intermediates for inhibitors of HIV protease and method of prepa

1995-05-24

1998-02-17

Springer, David B.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

540484, 540485, 546226, 546243, 548530, 548543, 564342, 549 54, 549 74, 549467, 549491, C07D21500, C07D30932, C07D40106, C07C22100

Patent

active

057192871

ABSTRACT:
The present invention provides novel HIV protease inhibitors, pharmaceutical formulations containing those compounds and methods of their use.

REFERENCES:
Snieckus, Chemical Reviews, 90, 879-933 (1990).
Beak, et al., Tetrahedron, 39, 1983-1989 (1983).
Nahm and Weinreb, Tetrahedron Letters, 22, 3815-3818 (1981).
Fehrentz and Castro, Synthesis, No. 8, 676-678 (1983).
Roberts, N.A. et al., Science, 248, 358-361 (1990).
Tam, T.F. et al., Journal of Medicinal Chemistry, 35(7), 1318-1320 (3 Apr. 1992).
Young, S.G., et al., Journal of Medicinal Chemistry, 35(10), 1702-1709 (15 May 1992).
Huff, J.R., Journal of Medicinal Chemistry, 34(8), 2305-2314 (Aug. 1991).

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