Intermediates for D-biotin synthesis and their production

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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C07D49504

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active

052470954

ABSTRACT:
There are disclosed a compound of the general formula (I): ##STR1## wherein the group R--CO-- is an acyl group and its production. There is also disclosed a process for producing optically active (.+-.)-(3a.alpha., 4.alpha., 6a.alpha.)-tetrahydro-4-acetoxy-1,3-dibenzyl-1H-thieno[3,4-d]imidazol-2(3H )-one by using the compound (I). The compound (I) can be used as an intermediate for producing D-biotin which is useful as medicaments and feed additives for animals.

REFERENCES:
Tetrahedron, vol. 46, No. 23, 1990 (printed in Great Britain), pp. 7677-7676.

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