Intermediates for cephalosporin compounds

Details Intermediates for cephalosporin compounds Intermediates for cephalosporin compounds

1991-07-19

1992-06-30

Rizzo, Nicholas S.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

540221, 540224, 540205, C07D50122, A61K 31545

Patent

active

051264447

ABSTRACT:
Cephalosporin antibiotics having a 3-position substituent of the formula: ##STR1## are described; wherein R.sup.1 is hydrogen or certain substituted alkyl groups, Z is CH or N, R.sup.2 and R.sup.3 are hydroxy or in vivo hydrolysable esters thereof, (R.sup.12).sub.n represents various optional substituents and X=Y is an olefin, oxime, azo or related group. Processes for their preparation and use are described.

REFERENCES:
patent: 5013730 (1991-05-01), Arnould et al.
patent: 5019570 (1991-05-01), Arnould et al.

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