Intermediates for .beta.-lactam compounds

Details Intermediates for .beta.-lactam compounds Intermediates for .beta.-lactam compounds

1990-05-18

1992-10-06

Rizzo, Nicholas S.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D49900

Patent

active

051533154

ABSTRACT:
The invention relates to an improved process for the preparation of compounds of formula ##STR1## or salts thereof, starting from compounds of formulae ##STR2## via compounds of formulae ##STR3## in which compounds R.sub.1 is hydrogen or lower alkyl, R.sub.2 is an organic radical which may carry a functional group which may be protected by a customary protective group R.sub.2 .degree., R.sub.3 is hydrogen or a customary carboxyl protective group R.sub.3 .degree., W is a group which can be replaced by a thiocarboxylic acid radical of formula III, and Z is oxygen or sulfur.

REFERENCES:
patent: 4347183 (1982-08-01), Alfonso et al.
patent: 4540579 (1985-09-01), Alfonso et al.
patent: 4656165 (1987-04-01), Lang
patent: 4962196 (1990-10-01), Hungerbuhler et al.
Chemical Abstracts vol. 107:58743P (1987).
Chemical Abstracts vol. 109 73244M (1988).
Alfonso et al. J. Amer. Chem. Soc. vol. 104, pp. 6138-6139 (1982).

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