Intermediates for 2-(1-oxo-3-thiolanyl)-2-penem antibiotics

Details Intermediates for 2-(1-oxo-3-thiolanyl)-2-penem antibiotics Intermediates for 2-(1-oxo-3-thiolanyl)-2-penem antibiotics

1986-06-24

1988-04-19

Rizzo, Nicholas S.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D49900, A61K 31425

Patent

active

047390476

ABSTRACT:
Process and intermediates for the conversion of 3R,4R-4-acetoxy-3-[1R-1-(silyloxy)ethyl]-2-azetidinones to antibacterial 5R,6S-6-(1R-1-hydroxyethyl)-2-(1-oxo-3-thiolanylthio)-2-penem-3-carboxylic acids, and the pharmaceutically-acceptable salts and pivaloyloxymethyl esters thereof.

REFERENCES:
patent: 4530793 (1985-07-01), Girijavallabhan et al.
patent: 4619924 (1986-10-01), Hamanako

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