Intermediates for 1,2-dideoxy-2-fluoronojirimycin

Details Intermediates for 1,2-dideoxy-2-fluoronojirimycin Intermediates for 1,2-dideoxy-2-fluoronojirimycin

1991-03-22

1992-12-29

Dentz, Bernard

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514302, 546 80, 546116, A61K 31345, C07D49114

Patent

active

051751682

ABSTRACT:
Novel compounds represented by the formula: ##STR1## wherein R represents hydrogen, optionally substituted alkyl radicals having from 1 to about 10 carbon atoms, optionally substituted alkenyl radicals having from 1 to about 10 carbon atoms, optionally substituted aryl, alkaryl and aralkyl radicals having from about 6 to about 16 carbon atoms and optionally substituted acyl and acyloxy radicals having from about 1 to about 10 carbon atoms, manifest glycosidase inhibition activity.

REFERENCES:
patent: 4348402 (1982-09-01), Kinast et al.
Stanek et al., The Monosaccharides, Academic Press, New York, pp. 186-187 & 365-374.
Truscheit et al., Angew. Chem. Int. Ed. English, vol. 20, pp. 744-761 (1981).
Munavu et al., J. Org. Chem., 41, 1831 (1976).
David et al., Tetrahedron, 41, (4), 643 (1985).
Tsuda et al., Chem. Pharm. Bull., 31 (5), 1612 (1983).
Boshagan et al., Carbohydrate Research, 164, 141 (1987).

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