Intermediates and methods for preparing 7-acylamino-8-oxo-oxa-1-

Details Intermediates and methods for preparing 7-acylamino-8-oxo-oxa-1- Intermediates and methods for preparing 7-acylamino-8-oxo-oxa-1-

1977-08-08

1978-10-24

Randolph, John D.

Organic compounds -- part of the class 532-570 series

Organic compounds

Chalcogen in the nitrogen containing substituent

42424852, 42424854, 260239A, 42424851, 4242485, C07D26504

Patent

active

041222628

ABSTRACT:
Intermediates and methods for preparing a new series of 7-acylamino-8-oxo-3-oxa-1-azabicyclo[4.2.0]-octane-2-carboxylic acid derivatives are described. The end product compounds have antibacterial activity especially against certain Gram negative organisms.

REFERENCES:
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patent: 4012383 (1977-03-01), Belleau et al.
patent: 4013653 (1977-03-01), Wolfe
patent: 4068075 (1978-01-01), Menard et al.
patent: 4068078 (1978-01-01), Menard et al.
patent: 4068080 (1978-01-01), Menard et al.
Cama et al., J. Am. Chem. Soc., vol. 96, pp. 7582 to 7584 (1974).
Guthikonda et al., J. Am. Chem. Soc., vol. 96, pp. 7584 to 7585 (1974).
Christensen et al., Chemical Abstracts, vol. 81, abst. 37560f (1974) (abst. of Ger. Offen 2,355,209).
Chemical Abstracts, vol. 83, p. 3592 CS (1975).
Aue et al., Chemical Abstracts, vol. 83, abst. No. 130785j (1975).
Chemical Abstracts, vol. 84, abst. No. 180,239a (1976).

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