Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1989-09-15
1990-03-27
Schwartz, Richard A.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
C07D40312
Patent
active
049122266
ABSTRACT:
Potent dopamine-.beta.-hydroxylase inhibitors having the Formula ##STR1## that are useful to inhibit dopamine-.beta.-hydroxylase activity, pharmaceutical compositions including these inhibitors, and methods of using these inhibitors to inhibit dopamine-.beta.-hydroxylase activity in mammals. Also disclosed are novel intermediates useful in preparing the presently invented inhibitors.
REFERENCES:
patent: 3941803 (1976-03-01), Gall
patent: 4554357 (1985-11-01), Verbicky et al.
Kruse Lawrence I.
Ohlstein Eliot H.
Ross Stephen T.
Lourie Alan D.
McCarthy Mary E.
Schwartz Richard A.
SmithKline Beckman Corporation
Suter Stuart R.
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