Intermediate, its synthesis, and its use in a process for the pr

Details Intermediate, its synthesis, and its use in a process for the pr Intermediate, its synthesis, and its use in a process for the pr

1984-08-30

1987-01-27

Jiles, Henry R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

568652, C07D30786, C07C 4323

Patent

active

046395369

ABSTRACT:
2,3-Dihydro-2,2-dimethyl-7-hydroxybenzofuran is prepared by reacting catechol with isobutylene oxide or with a compound having the general formula ##STR1## wherein R is halogen or hydroxyl, and X is halogen, in the presence of a base to form the intermediate 2-(2-hydroxy-2-methylpropoxy) phenol and then thermally dehydrating, rearranging and cyclizing the resulting intermediate phenol in the presence of an acid catalyst to form 2,3-dihydro-2,2-dimethyl-7-hydroxybenzofuran.

REFERENCES:
patent: 3274260 (1966-09-01), Levy et al.
patent: 3474170 (1969-10-01), Scharpf
patent: 3927118 (1975-12-01), Ozretich
patent: 4118400 (1978-10-01), Michaely
patent: 4250333 (1981-02-01), Rakoutz
patent: 4252985 (1981-02-01), Rakoutz
patent: 4314086 (1982-02-01), Soula et al.
patent: 4321204 (1982-03-01), Buttner et al.
patent: 4380654 (1983-04-01), Franko-Fillipasic et al.
Rindfusz, J.A.C.S., vol. 41, pp. 665-670 (1919).
J. Gripenberg and T. Hase, "The Ring Opening of Aromatic O-Heterocycles by Sodium in Pyridine," Acta Chem. Scand. 20: pp. 1561-1570 (1966) No. 6.

Affiliated with

Also associated with

Rating

Intermediate, its synthesis, and its use in a process for the pr does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Intermediate, its synthesis, and its use in a process for the pr, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Intermediate, its synthesis, and its use in a process for the pr will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-858880