Intermediate for (E)-4-[[3-[2-(4-cycloalkyl-2-thiazolyl)ethenyl]

Details Intermediate for (E)-4-[[3-[2-(4-cycloalkyl-2-thiazolyl)ethenyl] Intermediate for (E)-4-[[3-[2-(4-cycloalkyl-2-thiazolyl)ethenyl]

1996-05-28

1997-06-10

Gerstl, Robert

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548205, C07F 909

Patent

active

056377207

ABSTRACT:
The invention relates to a process of making a compound of the formula ##STR1## wherein R.sub.1, R.sub.2, R.sub.3 and R.sub.4 and n are as described herein, and, when R.sub.1 is different from R.sub.2, and/or when R.sub.3 is different from R.sub.4, enantiomers, diastereomers and racemates thereof, and salts thereof with pharmaceutically acceptable bases. The method comprises reacting a compound of the formula ##STR2## wherein R.sub.5 and n are as described herein with a compound of the formula ##STR3## to produce a compound of the formula ##STR4## wherein n is as described herein, and converting a compound of formula IV to a compound of formula I.

REFERENCES:
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