Intermediate compounds useful in the synthesis of kainic acid

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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5483121, 548465, 546272, C07D20952

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active

053527992

ABSTRACT:
The present invention provides processes for the synthesis of kainic acid. More specifically, the present invention is directed to a process for preparing a compound of the formula ##STR1## wherein R.sub.1 is hydrogen, acyl, alkoxycarbonyl, or arylalkoxycarbonyl;

REFERENCES:
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Murakami, Hasegawa, Hayashi, and Ito, "Synthesis of (+)-a-Allokainic Acid via the Zinc Acetate Catalyzed Cyclization of .gamma.-Isocyano Silyl Enolates", J. Org. Chem., 56, 7356 (1991).
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