Intermediate compounds for the preparation of trans...

Details Intermediate compounds for the preparation of trans... Intermediate compounds for the preparation of trans...

2011-06-07

2011-06-07

Shameem, Golam M (Department: 1626)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C549S200000, C549S346000, C548S421000

Reexamination Certificate

active

07956202

ABSTRACT:
Disclosed are novel amino acid derivatives of formula (I) and (II)processes for the preparation thereof, and their use in the preparation of trans-5-chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenz[2,3:6,7]oxepino-[4,5-c]pyrrole.

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DeBoer et al., Org-5222“Antipsychotic Dopamine D2 Receptor Antagonist 5-HT2 Receptor Antagonist”, Drugs of the Future, vol. 18, pp. 1117-1120, 1993.
Funke et al., Physico-Chemical Properties and Stability of Trans-5-Chloro-2-Methyl-2,3,3a,12b-Tetrahydro-1H-Dibenz [2,3;6,7]Oxepino[4,5-c]Pyrrolidine Maleate, Arzneim-Forsch, Drug Research, vol. 40, pp. 556-539, 1990.
Vader et al., “The Syntheses of Radiolabelled Org 52222 and its Main Metabolite Org 30526,” Journal of Labelled Compounds and Radiopharm, vol. 34, pp. 845-869, 1994.
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