Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2011-01-18
2011-01-18
Havlin, Robert (Department: 1626)
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
C514S410000
Reexamination Certificate
active
07872147
ABSTRACT:
Disclosed are novel amino acid derivatives of formula (I) and (II)processes for the preparation thereof, and their use in the preparation of trans-5-chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenz[2,3:6,7]oxepino-[4,5-c]pyrrole.
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Mar. (March;s Advanced Organic Chemistry, 5th ed., Eds. Smith and March, chapter 16 provided, 2001).
De Boer, Th. et al., Org-5222 “Antipsychotic Dopamine D2Receptor Antagonist 5-HT2Receptor Antagonist,” Drugs of the Future, vol. 18, No. 12 (1993) pp. 1117-1123.
Funke, C. W. et al., “Physico-chemical Properties and Stability of trans-5-Chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrolidine Maleate,” Arzneim.-Forsch./Drug Res., vol. 40, No. 5 (1990) pp. 536-539.
Vader, J. et al. “The Syntheses of Radiolabelled Org 5222 and its Main Metabolite Org 30526,” Journal of Labelled Compounds and Radiopharm., vol. 34, No. 9 (1994), pp. 845-869.
European Search Report for Application No. EP 06 11 2333 dated May 29, 2006.
Kemperman Gerardus Johannes
Reeder Michael R.
Van Der Linden Jacobus Johannes Maria
Devlin Gerard
Fischer H. Eric
Havlin Robert
N. V. Organon
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