Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...
Patent
1988-05-12
1990-02-13
Lee, Mary C.
Organic compounds -- part of the class 532-570 series
Organic compounds
Nitrogen attached directly or indirectly to the purine ring...
C07D23902
Patent
active
049008285
ABSTRACT:
A method for the synthesis of 2',3'-dideoxycytidine comprising a novel procedure of bromoacetylating cytidine to yield novel intermediates which are subsequently reduced and hydrogenated by novel procedures to yield 2',3'-dideoxycytidine.
REFERENCES:
patent: 4604382 (1983-01-01), Lin et al.
Adachi et al., Journal of Organic Chemistry, 44:9, 1404 (1979).
Tetrahedron Letters, 29, 11:1239 (1988).
Ashe et al., The Journal of Organic Chemistry, 44(9):1409 (1979).
Lin et al., The Journal of Medicinal Chemistry, 21(1):106 (1978).
Lin et al., The Journal of Medicinal Chemistry, 26(4):544 (1983).
Kranitsky et al., Journal of Medicinal Chemistry, 26(6):891 (1983).
Lin et al., The Journal of Medicinal Chemistry, 26(12):1691.
Samukov et al., Chemical Abstracts, 98:161094x (1983).
Marumoto et al., Chem. Pharm. Bulletin, 22(2):342 (1974).
Horowitz et al., Journal of Organic Chemistry, 32:817 (1967).
Prisbee et al., Synthetic Communications, 15(5):401 (1985).
Corey et al., Tetrahedron Letters, 23(19):1979 (1982).
Schroeder et al., Journal of Medicinal Chemistry, 24(9):1078 (1981).
Niedballa et al., Journal of Organic Chemistry, 39(25):3654 (1974).
Vorbruggen et al., Chem. Ber., 114:1234 (1981).
Fleet et al., Tetrahedron Letters, 28(31):3615 (1987).
Belica Peter S.
Huang Tai-Nang
Manchand Percy S.
Partridge John J.
Tam Steve
Epstein William H.
Gould George M.
Hoffmann-La-Roche Inc.
Lee Mary C.
Prlina Julie M.
LandOfFree
Intermediate compounds and an improved procedure for the synthes does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Intermediate compounds and an improved procedure for the synthes, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Intermediate compounds and an improved procedure for the synthes will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1169162