Interleukin converting enzyme inhibitors

Details Interleukin converting enzyme inhibitors Interleukin converting enzyme inhibitors

2006-02-21

2006-02-21

Kifle, Bruck (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C514S212080, C540S524000, C540S527000

Reexamination Certificate

active

07001899

ABSTRACT:
The present invention relates to novel compounds, compositions comprising said compounds, and uses thereof, said compounds having the formula:wherein each X is independently selected from:i) —C(W)2—;ii) —C(O)—;iii) —NR2—;iv) —S—;v) —S(O)—;vi) —S(O)2—;vii) two units, one from each adjacent X unit, can be taken together to form a substituted or unsubstituted double bond having the formula —CW═CW—; wherein each W is hydrogen of a unit having the formula —(L2)j—R2, the index j is 0 or 1;R is a carbocyclic or heterocyclic aryl ring;R1is a cysteine trap;each R2is independently a suitable substituent; andL, L1, and L2are linking units.

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