Interleukin-6 suppressive agent

Details Interleukin-6 suppressive agent Interleukin-6 suppressive agent

2007-10-16

2007-10-16

Lilling, Herbert J. (Department: 1657)

Drug, bio-affecting and body treating compositions

Enzyme or coenzyme containing

Oxidoreductases

C424S439000, C514S714000

Reexamination Certificate

active

10518018

ABSTRACT:
An interleukin-6 suppressive agent comprising lactoperoxidase as an active ingredient is used as a pharmaceutical preparation or the like for prevention and/or therapy of a disease caused by production of interleukin-6, such as thrombocytosis, myeloma, Castleman syndrome, rheumatoid arthritis, or influenza-virus infectious disease.

REFERENCES:
patent: 5561109 (1996-10-01), Mita et al.
patent: 2002/0044989 (2002-04-01), Gaull
patent: 2002/0192296 (2002-12-01), Gaull et al.
patent: 2003/0012787 (2003-01-01), Ashkenazi et al.
patent: 2003/0027248 (2003-02-01), Bejanin et al.
patent: 0 791 359 (1997-08-01), None
patent: 1 002 542 (2000-05-01), None
patent: 61-83131 (1986-04-01), None
patent: 3-218318 (1991-09-01), None
patent: 05-009124 (1993-01-01), None
patent: 05-092927 (1993-04-01), None
patent: 05-124980 (1993-05-01), None
patent: 6-501453 (1994-02-01), None
patent: 2840795 (1998-10-01), None
patent: 2000-509367 (2000-07-01), None
patent: 2001-226289 (2001-08-01), None
patent: 2002-238554 (2002-08-01), None
patent: WO92/01466 (1992-02-01), None
Lefkowitz, et al. “Induction of Tumor Necrosis Factor and Cytotoxicity by Macrophages Exposed to Lactoperoxidase and Microperoxidase,”Life Sciences, vol. 47, No. 8, pp. 703-709, 1990.
Lefkowitz, et al. “Peroxidase-Induced Enhancement of Chemiluminescence by Murine Peritoneal Macrophages,”Life Sciences, vol. 43, No. 9, pp. 739-745, 1988.
Shin, et al. “Identification of Lactoperoxidase in Mature Human Milk,”Journal of Nutritional Biochemistry, vol. 11, pp. 94-102, Feb. 2000.
Wong, et al. “Immunomodulatory Activities of Whey Fractions in Efferent Prefemoral Lymph of Sheep,”Journal of Dairy Research, vol. 63, pp. 257-267, 1996.
Wong, et al. “Influence of Whey and Purified Whey Proteins on Neutrophil Functions in Sheep,”Journal of Dairy Research, vol. 65, pp. 281-288, 1997.
Wong, et al. “Effects of Purified Bovine Whey Factors on Cellular Immune Functions in Ruminants,”Veterinary Immunology and Immunopathology, vol. 56, pp. 85-96, 1997.
Haversen, et al. “Human Lactoferrin and Peptides Derived from a Surface-Exposed Helical Region Reduce ExperimentalEscherichia coliUrinary Tract Infection in Mice,”Infection and Immunity, pp. 5816-5823, Oct. 2000.

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