Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Enzymatic production of a protein or polypeptide
Patent
1983-01-31
1987-07-28
Wiseman, Thomas G.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Enzymatic production of a protein or polypeptide
4351722, 435240, 435948, 530351, 530828, 514 2, 514 8, 514 12, C12P 2100, C12N 1500, C12N 500, C12R 191
Patent
active
046831991
ABSTRACT:
Interleukin-2 dependent cytotoxic cultured T-cell lines are found to produce .alpha., .beta., and .gamma. interferon, as well as interleukin-2, when stimulated by mitogenic or antigenic agents.
REFERENCES:
patent: 4285929 (1981-08-01), Sugimoto et al.
Wiranowska-Stewart et al, J. Interferon Res., vol. 1 (2), 1981, "Determination of Human Leukocyte Population Involved in Production of Interferons Alpha and Gamma".
Farrar et al, from Lymphokines, vol. 5, Editor Edgar Pick, 1982, Academic Press, pp. 355-358.
Marcucci et al. "Production of Immune Interferon by Murine T cell Clones from Long Term Cultures" Nature vol. 291, pp. 79-81, May 7, 1981.
Klein et al, "Cytotoxic T Lymphocytes Produce Immune Interferon in Response to Antigen or Mitogen", J. Exp. Med., vol. 155, pp. 1198-1203, Apr. 1982.
McKimm-Breschkin et al, "Antigen-Specific Production of Immune Interferon by T cell Kinesires", J. Exp. Med. vol. 155, pp. 1204-1209, Apr. 1982.
DeLeo et al, "Cell Surface Antigens of Chemically Induced Sarcomas of the Mouse", J. Exp. Med. vol. 146, pp. 720-734, 1977.
Braciale et al; "Heterogeneity and Specificity of Cloned Lines of Influenza-Virus-Specificytotoxic T Lymphocytes", J. Exp. Med. vol. 153, pp. 910-923, Apr. 1981.
Duprez, et al; "Cell-Mediated Anti-Tumor Response in the RL.male.1 System" European J. Immunology, vol. 8, pp. 650-655, Sep. 1978.
Nakayama, et al, "Definition of a Unique Cell Surface Antigen of Mouse Leukemia RL.male.1 by Cell Mediated Cytotoxicity", Proc. Natl. Acad. Sci, vol. 76, No. 7, pp. 3486-3490, Jul. 1979.
Gillis et al, "Long Term Culture of Tumor-Specific Cytotoxic T Cells", Nature vol. 268, pp. 154-156, Jul. 14, 1977.
Sloan-Kettering Institute for Cancer Research
Teskin Robin Lyn
White John P.
Wiseman Thomas G.
LandOfFree
Interleukin-2 dependent cytotoxic T-cell clones does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Interleukin-2 dependent cytotoxic T-cell clones, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Interleukin-2 dependent cytotoxic T-cell clones will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2034848