Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Using tissue cell culture to make a protein or polypeptide
Reexamination Certificate
2006-11-28
2006-11-28
Nickol, Gary B. (Department: 1646)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Using tissue cell culture to make a protein or polypeptide
C530S333000, C530S412000, C530S350000, C514S002600
Reexamination Certificate
active
07141393
ABSTRACT:
Disclosed are a receptor protein which recognize a novel cytokine, i.e., interleukin-18, a monoclonal antibody specific to the protein, and uses thereof. The receptor protein is useful as pharmaceutical to treat and prevent autoimmune and allergic disease because it suppresses and regulates excessive immunoreaction. The monoclonal antibody specifically reacts with interleukin-18, exhibiting efficacy in purification, detection and inhibition of interleukin-18.
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Kunikata Toshio
Kurimoto Masashi
Torigoe Kakuji
Ushio Shimpei
Browdy & Neimark PLLC
Jiang Dong
Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo
Nickol Gary B.
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