Interleukin-1β converting enzyme inhibitors

Details Interleukin-1β converting enzyme inhibitors Interleukin-1β converting enzyme inhibitors

2006-11-21

2006-11-21

Kifle, Bruck (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C514S249000, C514S299000, C540S461000

Reexamination Certificate

active

07138395

ABSTRACT:
The present invention relates to novel compounds, compositions comprising said compounds, and uses thereof, said compounds having the formula:X is —CH2—, —O— or —NR9—;R is a carbocyclic or heterocyclic ring;R1is a cysteine trap;R2a, R2a′, R2b, and R2b′are each independently hydrogen, C1–C4alkyl, C1–C4alkoxy, and mixtures thereof; or R2a′and R2b′can taken together to form a double bond; R9is hydrogen or a unit having the formula -L2-R10; L is the same as defined herein above; R10is hydrogen; substituted or unsubstituted C1–C6linear; branched, or cyclic hydrocarbyl; substituted or unsubstituted aryl; substituted or unsubstituted C1–C9heterocyclic; and substituted or unsubstituted heteroaryl.

REFERENCES:
patent: 5716929 (1998-02-01), Bemis et al.
patent: 5973111 (1999-10-01), Bemis et al.
patent: 6025147 (2000-02-01), Bemis et al.
patent: 6103711 (2000-08-01), Bemis et al.
patent: WO 98/32766 (1998-07-01), None
patent: WO 98/50032 (1998-11-01), None
patent: WO 02/081420 (2002-10-01), None

Affiliated with

Also associated with

Rating

Interleukin-1β converting enzyme inhibitors does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Interleukin-1β converting enzyme inhibitors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Interleukin-1β converting enzyme inhibitors will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3697918