Interleukin-1 receptor intracellular ligand proteins

Details Interleukin-1 receptor intracellular ligand proteins Interleukin-1 receptor intracellular ligand proteins

1996-10-07

1999-11-09

Mertz, Prema

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

530350, 435 691, 435 711, 435 712, 4351723, 4352523, 4353201, C07K 1447, C12N 1512, C12N 1563

Patent

active

059814829

ABSTRACT:
Novel IL-1-R intracellular ligand proteins are disclosed. Polynucleotides encoding the IL-1-R intracellular ligand protein are also disclosed, along with vectors, host cells, and methods of making the IL-1-R intracellular ligand protein. Pharmaceutical compositions containing the IL-1-R intracellular ligand protein, methods of treating inflammatory conditions, and methods of inhibiting IL-1-R intracellular domain binding are also disclosed. Methods of identifying inhibitors of IL-1-R intracellular domain binding and inhibitors identified by such methods are also disclosed.

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