Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1998-03-16
2000-10-24
Jones, Dwayne C.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514 17, 514 19, 530330, 530331, 530886, A61R 3800
Patent
active
061367877
ABSTRACT:
There is disclosed an isolated polypeptide and derivatives thereof having protease biological activity for human precursor IL-1.beta. and for a substrate comprising:
REFERENCES:
patent: 5756465 (1998-05-01), Sleath et al.
CAPLUS DN 116: 50949, Rosenthal et al., J. Clin. Invest., 88(5), 1467-72 (Abstract), 1991.
CAPLUS DN 118: 208112, Thornberry et al., Nature, (London), 356 (6372), 768-74 (Abstract), 1992.
Black Roy A.
Kronheim Shirley R.
Sleath Paul R.
Dixon Lisa A.
Haley, Jr. James F.
Jones Dwayne C.
Vertex Pharmaceuticals Incorporated
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