Interleukin 1.beta. protease and interleukin 1.beta. protease in

Details Interleukin 1.beta. protease and interleukin 1.beta. protease in Interleukin 1.beta. protease and interleukin 1.beta. protease in

1995-05-12

1998-05-26

Furman, Keith C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 18, 530329, 530330, C07K 704, C07K 706, A61K 3808, A61K 3817

Patent

active

057564655

ABSTRACT:
There is disclosed an isolated polypeptide and derivatives thereof having protease biological activity for human precursor IL-1.beta. and for a substrate comprising:

REFERENCES:
patent: 5104853 (1992-04-01), Beason et al.
patent: 5225354 (1993-07-01), Knowles et al.
patent: 5304481 (1994-04-01), Davies et al.
Sigma Catalog 1989 pp. 294-295, 312, 351-352.
Black et al "A Pre-asparte-specific Protease . . . ", Journal of Biological Chemistry vol. 264, No. 10 pp. 5323-5326 Apr. 5, 1989.
Malek et al. "Amino acid sequence . . . " Biochem Biophys Res Comm. 126(1) 1985 pp. 199-205 (Abstract only).
Knittel et al. "Stimulation of insulin . . . " Pept. Res. 3(5) 1990 pp. 224-227. (Abstract).
Kitada et al, "New peptide Model . . . " Chem Pharm Bull. 26(2) 1978 pp. 585-590. (Abstract).

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