Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Hydrolase
Patent
1994-02-28
1995-05-16
Patterson, Jr., Charles L.
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Hydrolase
495219, 536 232, 530351, C12N 964, C12N 1557
Patent
active
054160138
ABSTRACT:
There is disclosed an isolated polypeptide and derivatives thereof having protease biological activity for human precursor IL-1.beta. and for a substrate comprising:
REFERENCES:
Black R. A., et al. (1988) J. Biol. Chem. 263 (19), 9437-9442.
Suggs, S. V., et al, (1981) Proc. Natl. Acad. Sci. USA, 78(11), 6613-6617.
Cheremisinoff, et al. (ed) (1985) Biotechnology Applications and Research, Technomic Pub. Co. Inc, pp. 21, 541-557.
Black, R. A., et al. (1989) Febs Lett. 247 (2), 386-390.
Black, R. A., et al. (1989) J. Biol. Chem. 264 (10), 5323-5326.
Young, R. A. et al, (1983) Science 232, 778-782.
Lee, C. C., et al. (1988) Science 239, 1288-1291.
Black Roy A.
Kronheim Shirley R.
Sleath Paul R.
Davis William J.
Patterson Jr. Charles L.
Rudman Gilbert W.
Sterling Winthrop Inc.
Wells Doreen M.
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