Interleukin 1.beta. protease and interleukin 1.beta. protease in

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Hydrolase

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495219, 536 232, 530351, C12N 964, C12N 1557

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active

054160138

ABSTRACT:
There is disclosed an isolated polypeptide and derivatives thereof having protease biological activity for human precursor IL-1.beta. and for a substrate comprising:

REFERENCES:
Black R. A., et al. (1988) J. Biol. Chem. 263 (19), 9437-9442.
Suggs, S. V., et al, (1981) Proc. Natl. Acad. Sci. USA, 78(11), 6613-6617.
Cheremisinoff, et al. (ed) (1985) Biotechnology Applications and Research, Technomic Pub. Co. Inc, pp. 21, 541-557.
Black, R. A., et al. (1989) Febs Lett. 247 (2), 386-390.
Black, R. A., et al. (1989) J. Biol. Chem. 264 (10), 5323-5326.
Young, R. A. et al, (1983) Science 232, 778-782.
Lee, C. C., et al. (1988) Science 239, 1288-1291.

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