Interleukin-1 antagonist and uses thereof

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues

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530351, 435 691, 435 695, 435 6952, A61K 3816, A61K 3820, C07K 14545, C07K 14435

Patent

active

054553300

ABSTRACT:
Medicaments that have prophylactic or therapeutic applications for the treatment of disease resulting from the production of cytokines, particularly IL-1, that effectively inhibit the biological activity of the cytokines wherein the medicaments are characterized by being proteinaceous materials lacking a signal sequence for which a cDNA sequence has been identified and sequenced.

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Eisenberg, S. P., et al., 1990, Nature, 343:341-346.

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