Interferon stimulating protein and uses thereof

Details Interferon stimulating protein and uses thereof Interferon stimulating protein and uses thereof

1998-06-26

1999-12-14

MacMillan, Keith D.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

574 21, 574 2, 530350, 530324, 530325, A61K 3810

Patent

active

060018062

ABSTRACT:
This invention relates to the use of the baculovirus glycoprotein, Interferon Stimulating Protein (ISP) (also known as gp67, gp64 EFP, or gp64), or the gene sequence encoding ISP, to stimulate production of interferon, such as for immunotherapy, anti-viral, anti-cancer, anti-bacterial, or anti-parasitic therapy. This invention also relates to novel mutant forms of ISP that show enhanced biological (i.e., anti-viral) activity, increased stability, higher yield or better solubility.

REFERENCES:
patent: 5750383 (1998-05-01), Blissard et al.
patent: 5770192 (1998-06-01), Cayley et al.
patent: 5846714 (1998-12-01), Haskill et al.
patent: 5871986 (1999-02-01), Boyce
Whitford, M. et al., J. Of Virology, 63(3):1393-1399 (Mar. 1989)
Genbank entry, Accession No. AAA72760.
Genbank entry, Accession No. AAA66758.

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