Interferon purification process

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Lymphokines – e.g. – interferons – interlukins – etc.

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Details

424 854, 424 857, C07K 1526, C07K 320, A61K 4502

Patent

active

053917138

ABSTRACT:
A process for purification of human leukocyte interferon is described. The process includes immunoaffinity chromatography, ion-exchange chromatography, and a series of precipitation and centrifugation steps.

REFERENCES:
patent: 3414651 (1968-12-01), Fantes
patent: 4474754 (1984-10-01), Shimizu et al.
patent: 4873312 (1989-10-01), Arakawa

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