Interferon product and process for its preparation

Details Interferon product and process for its preparation Interferon product and process for its preparation

1978-10-27

1981-06-16

Phillips, Delbert R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424 85, A61K 4502, A61K 3700, C07G 700

Patent

active

042737036

ABSTRACT:
Exogenic porcine interferon for administration in human beings. The porcine interferon shows antiviral protecting activity on cultured human cells and is substantially free of any immunoelectrophoresis bands which are not identical or partially identical with bands in human leucocyte interferon or human agammaserum. A process for preparing the porcine interferon by harvesting, isolating and, if desired, priming porcine leucocytes, treating them with an interferon inductor and incubating them and obtaining the interferon formed, the process being characterized in using, as added protein source in any of the said stages, a source which is substantially free of immunoelectrophoresis band which are not identical or partially identical with bands in human agammaserum.

REFERENCES:
Chemical Abstracts, vol. 77 (1972), p. 111830e-111831f.
Mogensen et al., "Pharm. Ther. A.," vol. 1 (1977), p. 369-381.
Gresser et al., "Nature, " vol. 251 (1974), p. 543-545.
Toneva, Venera, Proc. of 3rd Int. Pig Veterinary Society Congress, Lyon (1974).
Chem. Abstr., vol. 73, 33425c (1970).
Chem. Abstr., vol., 71, 68903t (1969).
Chem. Abstr., vol. 78, 122444d (1973).
Chem. Abstr., vol. 72, 10984z (1970).
Microb. Abstr., Section A, vol. 8, No. 7, 90-91 8A5062 (1973).
Chem. Abstr., vol. 78, 68982n (1973).

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