Interferon polymer conjugates

Details Interferon polymer conjugates Interferon polymer conjugates

1994-11-10

1998-01-27

Sayala, Chhaya D.

Drug, bio-affecting and body treating compositions

Lymphokine

Interferon

530402, A61K 3821

Patent

active

057119449

ABSTRACT:
A process is disclosed for preparing long-acting alpha interferon-containing compositions. Alpha interferon is contacted with a relatively small molar excess of a substantially non-antigenic polymer in the presence of a surfactant to preserve bioactivity. Isolation of the desired conjugate species having optimal activity is also disclosed.

REFERENCES:
patent: 4179337 (1979-12-01), Davis et al.
patent: 4275000 (1981-06-01), Ross
patent: 4609546 (1986-09-01), Hiratani
patent: 4680338 (1987-07-01), Sundoro
patent: 4766106 (1988-08-01), Katre et al.
patent: 4894226 (1990-01-01), Aldwin et al.
patent: 4904582 (1990-02-01), Tullis
patent: 4917888 (1990-04-01), Katre et al.
patent: 4935465 (1990-06-01), Garman
patent: 5004605 (1991-04-01), Hershenson et al.
patent: 5109120 (1992-04-01), Ueno et al.
patent: 5122614 (1992-06-01), Zalipsky
patent: 5281698 (1994-01-01), Nitecki
patent: 5283317 (1994-02-01), Saifer et al.
patent: 5382657 (1995-01-01), Karasiewicz et al.
patent: 5559213 (1996-09-01), Hakimi et al.
Zalipsky, et al., Attachment of Drugs to Polyethlene Glycols, Eur. Ploym. J., vol. 19, No. 12, pp. 1177-1183 (1983).

Affiliated with

Also associated with

Rating

Interferon polymer conjugates does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Interferon polymer conjugates, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Interferon polymer conjugates will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-339582