Interferon assay

Details Interferon assay Interferon assay

1978-11-24

1980-12-23

Wiseman, Thomas G.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving virus or bacteriophage

424 2, 424 85, 23230B, 435241, 435811, C12Q 170, C12N 502

Patent

active

042411742

ABSTRACT:
A rapid cytopathic effect inhibition assay for interferon is disclosed. The assay can be completed in about 16 hours or less, allowing its use to assist in clinical diagnosis of viral infections and also, in monitoring the production and purification of interferon whether leukocyte or fibroblast.

REFERENCES:
patent: 3910824 (1975-10-01), Cartwright et al.
Armstrong, "Semi-Micro Dye-Binding Assay for Rabbit Interferon", Applied Microbiology, vol. 21, No. 4, (1971), pp. 723-725.
Lindenmann, et al., "Studies on Vaccinia Virus Plaque Formation and Its Inhibition by Interferon", Virology, vol. 19, (1963), pp. 302-309.
Green, et al., "Vesicular Stomatitis Virus Plaque Production in Monolayer Cultures with Liquid Overlay Medium: Description and Adaptation to a One-Day, Human Interferon-Plaque Reduction Assay", J. Clin. Micro., vol. 4, No. 6, (1976), pp. 479-485.
Borden, et al., "A Quantitative Semi-Micro, Semi-Automated Colorimetric Assay for Interferon", J. Lab. Clin. Med., vol. 89, No. 5, (1977), pp. 1036-1042.
Suzuki, et al, "Rapid and Simple Method for Assaying Interferon", Chem. Abstracts, vol. 83, No. 9, p. 494, (1975), Abs. No. 76834j.

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