Interferon and preparations containing interferon

Details Interferon and preparations containing interferon Interferon and preparations containing interferon

1979-01-22

1981-06-30

Philips, Delbert R.

Drug, bio-affecting and body treating compositions

Lymphokine

435 68, 435811, A61K 4502, A61K 3900

Patent

active

042762820

ABSTRACT:
The present invention relates to processes for an easily applicable industrial production of interferon and the possibilities of the products for preventing and treating interferonsensitive diseases.
The process easily produces a large amount of interferon and transplanting established human cells to other warm-blooded animals or inoculating the cells in a diffusion chamber and multiplying the cells therein while allowing the animals to supply the cells with their nutrient body fluids, then exposing in vivo or in vitro the resultant cells to the action of interferon inducer. The present invention is also based on the discovery that the interferon obtained by the present method is an effective and superior preparation for preventing and treating interferon-sensitive diseases.

REFERENCES:
Chemical Abstracts, vol. 89, 105634a, 1978.
Chemical Abstracts, vol. 82, 14962v, 1975.
Chemical Abstracts, vol. 83, 25879v, 1975.
Miyoshi, I., et al., Cancer, vol. 40, pp. 2999-3003, 1977.
Miyoshi, I., et al., Nature, vol. 267, pp. 843-844, 1977.
Strander, H., et al., J. of Clin. Microbiol., vol. 1, pp. 116-117, 1975.
Finter, "Interferons," 1966, pp. 263-266, North Holland Pub. Co.
Miyoshi et al., Reprint from "Nature," vol. 267, No. 5614 (1977), pp. 843-844.
Science, vol. 204, pp. 1184-1185, Editorial, 1979.
Proteins, Nucleic Acid and Enzyme, vol. 21, No. 4, pp. 616-643, "The Current Situation of the Maintenance and Preservation of Tissue Culture Cell Lines in Japan".

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