Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1998-10-06
2000-05-09
Achutamurthy, Ponnathapu
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
43525233, 435325, 4353201, 536 231, 536 235, 530350, C12P 2106, C07H 2102, C07H 2104
Patent
active
060602791
ABSTRACT:
The present invention is directed to an isolated nucleic acid molecule encoding an interferon-.alpha.-induced protein, particularly the protein designated p36. Expression vectors and host cells comprising the nucleic acid molecule are also provided, as well as methods for increasing or decreasing the expression of the interferon-.alpha.-induced protein in host cells. DNA oligomers and antibodies specific for interferon-.alpha.-induced protein are provided, each of which can be used to detect interferon-.alpha.-induced protein in a sample. Methods for diagnosing immunodeficiency and autoimmune disease in an individual and methods for detecting the presence or past existence of lupus inclusions or interferon-.alpha. in a sample are also provided.
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Masters Paul S.
Rich Steven A.
Achutamurthy Ponnathapu
Health Research Incorporated
Nashed Nashaat T.
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