Interferon administration vehicles

Details Interferon administration vehicles Interferon administration vehicles

1987-03-12

1990-03-27

Hazel, Blondel

Drug, bio-affecting and body treating compositions

Lymphokine

Interferon

424 854, 424 855, 424 856, A61K 4502

Patent

active

049119087

ABSTRACT:
An interferon preparation to be administered topically is provided comprising: (a) a therapeutically effective amount of one or more interferons; (b) a vehicle base compatible with the interferon or interferons being administered; (c) an effective amount of one or more protease inhibitors for the purpose of reducing the rate of decay of the biological activity of the interferon or interferons due to proteolytic agents; and (d) an effective amount of one or more anti-microbial agents. In certain preferred embodiments of the invention, the vehicle base is prepared from a mixture of polyethylene glycols or includes hydroxyethyl cellulose as a thickening agent.

REFERENCES:
patent: 4348384 (1982-09-01), Horikoshi et al.
patent: 4478822 (1984-10-01), Haslam et al.
patent: 4507281 (1985-03-01), Asailai et al.

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