Interferometric measurement of glucose by refractive index deter

Optics: measuring and testing – By polarized light examination – With birefringent element

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356 36, G01B 902

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active

051683253

ABSTRACT:
An apparatus and method for testing the glucose level in a blood sample is provided. The method includes the step of initially filtering a sample of blood to be tested. A beam of light is provided and split into a pair of beams by a beam splitter. The pair of beams travel along generally parallel paths. One path contains a cell of a known optical pathlength and additionally a compensator. The other path has a cell containing the filtered blood sample to be tested. The pair of beams are then recombined by a mirror and a fringe pattern is detected at a detector. From the fringe pattern, the refractive index of the blood sample can be calculated. The refractive index is easily converted to a specific glucose concentration. Alternatively, the original fringe pattern can be restored by changing the effect of the compensator. The refractive index can then be found from the required compensation.

REFERENCES:
patent: 2434029 (1948-01-01), Williams
patent: 3825347 (1974-07-01), Kaiser
patent: 3963019 (1976-06-01), Quandt
patent: 4169676 (1979-10-01), Kaiser
patent: 4690562 (1987-09-01), Davies et al.
patent: 4704029 (1987-11-01), Van Heuvelen
Born et al., Principles of Optics, Pergamon Press, Oxford, pp. 269-271, 1980.

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