Interferometric detection system and method

Details Interferometric detection system and method Interferometric detection system and method

2008-05-16

2010-11-16

Toatley, Gregory J (Department: 2877)

Optics: measuring and testing

By light interference

For refractive indexing

Reexamination Certificate

active

07835013

ABSTRACT:
Disclosed are improved optical detection systems and methods comprising interferometric detection systems, methods for determining a characteristic property of a fluid, methods for calculating a shift between at least two signals, computer program products encoded in a computer readable medium, and computational systems. Also disclosed are label-free, free-solution, and/or real-time measurements of characteristic properties and/or chemical events using the disclosed techniques. Also disclosed are various biosensor applications of the disclosed techniques. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

REFERENCES:
patent: 4895431 (1990-01-01), Tsujiuchi et al.
patent: 4976154 (1990-12-01), Schneider et al.
patent: 4990925 (1991-02-01), Edelsohn et al.
patent: 5073024 (1991-12-01), Valette et al.
patent: 5120131 (1992-06-01), Lukosz
patent: 5273633 (1993-12-01), Wang et al.
patent: 5325170 (1994-06-01), Bornhop
patent: 5479257 (1995-12-01), Hashimoto
patent: 5485312 (1996-01-01), Horner et al.
patent: 5502561 (1996-03-01), Hutchins
patent: 5613013 (1997-03-01), Schuette
patent: 5659318 (1997-08-01), Madsen et al.
patent: 5781304 (1998-07-01), Kotidis et al.
patent: 5804453 (1998-09-01), Chen
patent: 5817462 (1998-10-01), Garini et al.
patent: 5915034 (1999-06-01), Nakajima et al.
patent: 5953439 (1999-09-01), Ishihara et al.
patent: 5995645 (1999-11-01), Soenksen et al.
patent: 6108458 (2000-08-01), Hart
patent: 6198532 (2001-03-01), Cabib et al.
patent: 6381025 (2002-04-01), Bornhop et al.
patent: 6480282 (2002-11-01), Chinowsky et al.
patent: 6493090 (2002-12-01), Lading et al.
patent: 6529279 (2003-03-01), de Groot et al.
patent: 6532061 (2003-03-01), Ortyn et al.
patent: 6533914 (2003-03-01), Liu
patent: 6741361 (2004-05-01), Marron
patent: 6744950 (2004-06-01), Aleksoff
patent: 6798509 (2004-09-01), Sonehara et al.
patent: 6809828 (2004-10-01), Bornhop et al.
patent: 6980299 (2005-12-01), de Boer
patent: 7130060 (2006-10-01), Bornhop et al.
patent: 7173986 (2007-02-01), Wu
patent: 7202076 (2007-04-01), Cunningham et al.
patent: 7300803 (2007-11-01), Lin et al.
patent: 2004/0058058 (2004-03-01), Shchegolikhin et al.
patent: 2005/0014179 (2005-01-01), Karlsson et al.
patent: 2005/0190372 (2005-09-01), Dogariu
patent: 2005/0227374 (2005-10-01), Cunningham
patent: 2005/0244863 (2005-11-01), Mir
patent: 2006/0012800 (2006-01-01), Bornhop et al.
patent: 2006/0039004 (2006-02-01), De Boer et al.
patent: 2006/0256343 (2006-11-01), Choma et al.
patent: 2007/0054339 (2007-03-01), Lin et al.
patent: 1746385 (2007-01-01), None
patent: 2 766 922 (1999-02-01), None
patent: WO 01/14858 (2001-03-01), None
patent: WO 2004/023115 (2004-03-01), None
patent: WO 2007/002178 (2007-01-01), None
International Search Report and Written Opinion for International Application No. PCT/US2008/63879, 2008.
EP, 08755681.7, May 16, 2008, Jones, Preliminary Amendment, Feb. 22, 2010.
PCT, PCT/US2008/63879, May 16, 2008, Jones, International Preliminary Report on Patentability, Nov. 24, 2009.
PCT, PCT/US2005/38168, Oct. 22, 2004, Bornhop, Written Opinion, Apr. 26, 2006.
PCT, PCT/US2005/38168, Oct. 22, 2004, Bornhop, International Search Report, Apr. 26, 2006.
PCT, PCT/US2005/38168, Oct. 22, 2004, Bornhop, International Preliminary Report on Patentability, Apr. 27, 2007.
PCT, PCT/US2008/077145, Sep. 20, 2008, Bornhop, Written Opinion, Dec. 8, 2008.
PCT, PCT/US2008/077145, Sep. 20, 2008, Bornhop, International Search Report, Dec. 8, 2008.
PCT, PCT/US2008/077145, Sep. 20, 2008, Bornhop, International Preliminary Report on Patentability, Mar. 24, 2010.
Jacobson, et al., “Fused Quartz Substrates for Microchip Electrophoresis,”Anal Chem, 67:2059-2063 (1995).
Liu, et al., “Optimization of high-speed DNA sequencing on microfabricated capillary electrophoresis channels,”Anal Chem, 71:566-573 (1999).
Manz, et al., “Micromachining of Monocrystalline Silicon and Glass for Chemical-Analysis Systems—a Look into Next Century Technology or Just a Fashionable Craze?,”Trac-Trends in Anal Chem, 10(5):144-149 (1991).
Markov, et al., “Breaking the 10-7 Barrier for RI Measurements in Nanoliter Volumes,” Anal Chem, 74:5438-5441 (2002).
Martynova, et al., “Fabrication of plastic microfluid channels by imprinting methods,”Anal Chem, 69:4783-4789 (1997).
May, et al., “Inverting enantioselectivity by directed evolution of hydantoinase for improved production of L-methionine,”Nat Biotech, 18(3):317-320 (2000).
Sorensen, et al., “Absolute refractive index determination by microinterferometric backscatter detection,”Anal Chem, 75:1946-1953 (2003).
Swinney, et al., “Micro-interferometric backscatter detection using a diode laser,”Analytica Chimica Acta, 400:265-280 (1999).
Theze, et al., “Interleukin 2 and its receptors: recent advances and new immunological functions,”Immunology Today17:481-486 (1996).
Brawer, et al., “Screening for prostatic carcinoma with prostate specific antigen,”J. Urol., 147:841-845 (1992).
Collignon et al., “Automated multimodality image registration based on information theory”, Information Processing in Medical Imaging (Y. Bizais, C. Barillot and R. Di Paola, eds.), Kluwer Academic Publishers, Dordrecht, pp. 263-274, 1995.
Fox, et al., “Assay Innovations Vital to Improving HTS,”Drug Discovery and Development, Mar. 2000:40-43.
Hofstetter, et al., “Antibodies as chiral selectors for the determination of enantioenrichment,”Enantiomer, 6:153-158 (2001).
Kuhlmann, “Drug Research: From the Idea to the Product,” Int J Clin Pharmacol Ther, 35(12):541-552 (1997).
Langone, “Protein A ofStaphylococcus aureusand related immunoglobulin receptors produced by streptococci and pneumonococci,”Adv Immunol, 32:157-252 (1982).
Swinney, et al., “Laser-Based Capillary Polarimetry,”J Capill Electrophor Microchip Technol, 6(3-4):93-96 (1999).
Viola et al., “Alignment by maximization of mutual information”, International Conference on Computer Vision (E. Grimson, S. Shafer, A. Blake and K. Sugihara, eds.), IEEE Computer Society Press, Los Alamitos, CA, pp. 16-23, 1995.
Yanik, et al., Development of a New Laser Based Polarimetric Detector and Its Application to High-performance Liquid Chromatography. PDR-Chiral, 1998.
Grant No. R01 EB003537-01A2 awarded by National Institutes of Health, 2004.
Abato, et al., “An enzymatic method for determining enantiomeric excess,”J Am Chem Soc, 123:9206-9207 (2001).
Adányi et al., “Development of immunosensor based on OWLS technique for determining Aflatoxin B1 and Ochratoxin A,”Biosens Bioelectron22:797-802 (2007).
Alunni, et al., “Mechanisms of inhibition of phenylalanine ammonia-lyase by phenol inhibitors and phenol/glycine synergistic inhibitors,”Arch Biochem and Biophys412(2):170-175 (2003).
Anderson, et al., “Fabrication of topologically complex three-dimensional microfluidic systems in PDMS by rapid prototyping,”Anal Chem72(14):3158-64 (2000).
Andersson et al., “TV shearography: quantitative measurement of shear-magnitude fields by use of digital speckle photography,” Applied Optics, vol. 39:2565 (2000).
Anuta, “Digital Registration of Multispectral Video Imagery,” Society of Photo-optical Instrumentation Engineers Journal, vol. 7:168 (1969).
Arnold, “Design by directed evolution,”Accounts Chem Res31(3):125-131 (1998).
Bobbitt, et al., “Direct and Indirect Polarimetry for Detection in Microbore Liquid-Chromatography,”Anal Chem56:1577-1581 (1984).
Borman, “Combinatorial chemistry,”Chem&Eng Newsvol. 80 No. 45:43-57 (2002).
Bornhop, “Microvolume index of refraction determinations by interferometric backscatter,”Applied Optics, vol. 34:3234-39 (1995).
Bornhop, et al., “Free-Solution, Label-Free Molecu

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