Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1984-12-05
1989-06-13
Warden, Robert I.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435 18, 436518, 436519, 436821, 436825, 436829, G01N 3353, G01N 33543, G01N 33554
Patent
active
048392766
ABSTRACT:
A method and reagent composition provide for the removal or blocking of serum interferences in liposome immunoassays. A carrier or liposome exhibiting at least one domain of phosphoryl ester groupings different from those of the marker liposome is introduced into the reaction mixture, whereby endogenous interfering species competitively bind to such carrier or liposome rather than to the marker liposome. Also, soluble phosphoryl ester groupings can be introduced into the reaction mixture which react with such endogenous species and further reduce serum interferences.
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Adolfsen Robert H.
Hedaya Eddie
Mak C. Lam
Schwarzberg Moshe
Greenman Jeffrey M.
Spiegel Jack
Technicon Instruments Corporation
Warden Robert I.
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