Interference free transaminase assay

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving transferase

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435 26, 435810, C12Q 152, C12Q 132

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active

045754888

ABSTRACT:
Compositions for pyridoxal-5'-phosphate (PLP) activated transaminase determinations are provided, in which interference due to PLP is avoided. Amino-functionalized polymers bind PLP which is not associated with the apotransaminase in the sample to be tested, thereby avoiding signal interference, e.g. background absorbance, due to PLP.

REFERENCES:
patent: 3458403 (1969-07-01), Katsunuma
patent: 4235962 (1980-11-01), Sanderson
patent: 4241179 (1980-12-01), Madappally et al.
patent: 4271265 (1981-06-01), Deneke et al.
patent: 4372874 (1983-02-01), Modrovich
patent: 4450232 (1984-05-01), Sanford et al.
Sanderson, Clin. Chem., 27(6):1035, Abst. 054 (1981).
Bergmeyer et al., Clin. Chem. 24(4):720-721, (1978).
Bergmeyer et al., Clin. Chem., 23(5):887-893, (1977).

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