Integrin targeted imaging agents

Details Integrin targeted imaging agents Integrin targeted imaging agents

2005-12-16

2008-03-18

Jones, D. L. (Department: 1618)

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

Coated, impregnated, or colloidal particulate

C424S001110, C424S001370, C424S001650, C424S009300, C424S009321, C534S015000

Reexamination Certificate

active

07344698

ABSTRACT:
Emulsions preferably of nanoparticles formed from high boiling liquid perfluorochemical substances, said particles coated with a lipid/surfactant coating are made specific to regions of activated endothelial cells by coupling said nanoparticles to a ligand specific for αvβ3integrin, other than an antibody. The nanoparticles may further include biologically active agents, radionuclides, or other imaging agents.

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