Integrin targeted imaging agents

Details Integrin targeted imaging agents Integrin targeted imaging agents

2007-08-14

2007-08-14

Jones, Dameron L. (Department: 1618)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Capsules

C424S009321, C424S009320, C424S009300

Reexamination Certificate

active

10351463

ABSTRACT:
Emulsions preferably of nanoparticles formed from high boiling liquid perfluorochemical substances, said particles coated with a lipid/surfactant coating are made specific to regions of activated endothelial cells by coupling said nanoparticles to a ligand specific for αvβ3integrin, other than an antibody. The nanoparticles may further include biologically active agents, radionuclides, or other imaging agents.

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