Integrin antagonists useful as anticancer agents

Details Integrin antagonists useful as anticancer agents Integrin antagonists useful as anticancer agents

2011-08-23

2011-08-23

Stockton, Laura L. (Department: 1626)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C514S242000, C514S258100, C514S259500, C514S307000, C514S311000, C514S322000, C514S338000, C514S365000, C514S378000, C514S252010, C514S255010, C514S361000, C514S394000, C544S182000, C544S238000, C544S262000, C544S333000, C544S370000, C546S146000, C546S169000, C546S199000, C546S273400, C548S127000, C548S181000, C548S248000

Reexamination Certificate

active

08003806

ABSTRACT:
The invention relates to compounds of the Formula 1and to pharmaceutically acceptable salts and solvates thereof, wherein A, X2, X4, X5and X1are as defined herein. The invention also relates to methods of treating abnormal cell growth in mammals by administering the compounds of Formula 1 and to pharmaceutical compositions for treating such disorders which contain the compounds of Formula 1.

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