Chemistry: molecular biology and microbiology – Process of mutation – cell fusion – or genetic modification – Introduction of a polynucleotide molecule into or...
Patent
1996-06-03
1999-11-23
Brusca, John S.
Chemistry: molecular biology and microbiology
Process of mutation, cell fusion, or genetic modification
Introduction of a polynucleotide molecule into or...
4353201, 536 231, C12N 1563, C12N 1511
Patent
active
059899140
ABSTRACT:
The present invention relates to DNA constructs provided to improve transgenesis or genomic integration of DNA fragment of interest into nuclear DNA of eukaryotic cell. The DNA constructs of the present invention allow a more efficient procedure by increasing the rate of genomic integration of a DNA fragment. After integration into host cell's DNA, the DNA constructs may provide a mean of screening transgenic cells. An increasing integration means, as well as a method for screening transgenic cells with said DNA construct are disclosed.
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Gagne Marc
Pothier Fran.cedilla.ois
Sirard Marc-Andre
Brusca John S.
Universite Laval
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