Optics: measuring and testing – By dispersed light spectroscopy – With sample excitation
Reexamination Certificate
2007-10-30
2007-10-30
Lauchman, Layla G. (Department: 2877)
Optics: measuring and testing
By dispersed light spectroscopy
With sample excitation
Reexamination Certificate
active
10842750
ABSTRACT:
An optical biosensor has a first enclosure with a pathogen recognition surface, including a planar optical waveguide and grating located in the first enclosure. An aperture is in the first enclosure for insertion of sample to be investigated to a position in close proximity to the pathogen recognition surface. A laser in the first enclosure includes means for aligning and means for modulating the laser, the laser having its light output directed toward said grating. Detection means are located in the first enclosure and in optical communication with the pathogen recognition surface for detecting pathogens after interrogation by the laser light and outputting the detection. Electronic means is located in the first enclosure and receives the detection for processing the detection and outputting information on the detection, and an electrical power supply is located in the first enclosure for supplying power to the laser, the detection means and the electronic means.
REFERENCES:
patent: 4447546 (1984-05-01), Hirschfeld
patent: 4558014 (1985-12-01), Hirschfeld
patent: 4582809 (1986-04-01), Block
patent: 4595833 (1986-06-01), Sting
patent: 4654532 (1987-03-01), Hirschfeld
patent: 4671938 (1987-06-01), Cook
patent: 4716121 (1987-12-01), Block
patent: 4844869 (1989-07-01), Glass
patent: 4852967 (1989-08-01), Cook
patent: 4909990 (1990-03-01), Block
patent: 5061857 (1991-10-01), Thompson
patent: 5152962 (1992-10-01), Lackie
patent: 5242797 (1993-09-01), Hirschfeld
patent: 5290398 (1994-03-01), Feldman
patent: 5359681 (1994-10-01), Jorgenson
patent: 5399866 (1995-03-01), Feldman
patent: 5430813 (1995-07-01), Anderson
patent: 5442448 (1995-08-01), Knoll
patent: 5468606 (1995-11-01), Bogart
patent: 5492674 (1996-02-01), Meserol
patent: 6136611 (2000-10-01), Saaski
patent: 6297059 (2001-10-01), Song
patent: 2005/0154277 (2005-07-01), Tang et al.
patent: 0 535 690 (1997-03-01), None
patent: WO90/09574 (1990-08-01), None
Grace et al. “Reagentless Optical Biosensor (ROB) Prototype”, http://www.zyn.com/flc/meeting/presentations/Grace.pdf, p. 10.
Yang et al. “A Novel Integrated Optical Sensor for DNA Arrays Detection”, SPIE vol. 4092, pp. 155-157.
Daniel Kelly, “Integrated Optical Biosensor,” U.S. Appl. No. 09/598,882, filed Jun. 21, 2000.
Xuedong Song, John Nolan, and Basil Swanson, “Optical Biosensor Based On Fluorescence Resonance Energy Transfer: Ultrasensitive and Apecific Detection Of Protein Toxins,” J. Am. Chem., vol. 120, pp. 11514-11515, 1998.
Karen Grace and Basil Swanson, “ROB: Reagentless Optical Biosensor,” 2003 R&D, 100 Entry, pp. 1-17, Mar. 1, 2003.
Goeller Roy M.
Grace Karen M.
Grace Wynne Kevin
Kolar Jerome D.
Morrison Leland Jean
Geisel Kara
Lauchman Layla G.
Los Alamos National Security LLC
Wyrick Milton D.
LandOfFree
Integrated optical biosensor system (IOBS) does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Integrated optical biosensor system (IOBS), we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Integrated optical biosensor system (IOBS) will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3881652