Integrase inhibitors containing aromatic heterocycle...

Details Integrase inhibitors containing aromatic heterocycle... Integrase inhibitors containing aromatic heterocycle...

2000-08-25

2009-08-18

Wessendorf, T. D. (Department: 1639)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C540S013000, C540S051000, C544S003000, C546S004000, C548S119000, C548S174000, C549S006000, C549S013000

Reexamination Certificate

active

07576198

ABSTRACT:
A compound of the formula (I):wherein X is hydroxy or the like;Y is —C(═R2)—R3—R4wherein R2and R3is oxygen atom or the like, R4is hydrogen, optionally substituted alkyl,optionally substituted heteroaryl or the like;Z is hydrogen or the like;Z1and Z3each is independently a bond, alkylene or the like;Z2is a bond, alkylene, —O— or the like;R1is optionally substituted aryl, optionally substituted heteroaryl or the like;p is 0 to 2 andring (A) is optionally substituted aromatic heterocycle, a tautomer of itself, a prodrug thereof, a pharmaceutically acceptable salt thereof or a solvate thereof has an integrase-inhibiting activity.

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