Integral multilayer analytical element for analysis of albumin

Details Integral multilayer analytical element for analysis of albumin Integral multilayer analytical element for analysis of albumin

1988-08-19

1991-05-07

Lacey, David L.

Chemical apparatus and process disinfecting, deodorizing, preser

Analyzer, structured indicator, or manipulative laboratory...

Calorimeter

422 57, 422 58, 436 71, G01N 2100

Patent

active

050135279

ABSTRACT:
In an integral multilayer analytical element for the analysis of albumin where at least one hydrophilic polymer binder layer and a porous spreading layer containing an indicator capable of binding to albumin to produce a color change are integrally superposed on a light-transmissive water-impermeable support in this order, the improvement comprising said indicator being dispersed in a hydrophilic polymer or a mixture of a hydrophilic polymer and a hydrophobic polymer and a pH buffer being incorporated into the spreading layer.
In the analytical element of the invention, the error caused by the competitive inhibition by globulin can be removed by making to produce the color due to the bonding between albumin and indicator relatively much in the support side (lower side) portion of the porous spreading layer and by making to produce the color due to the bonding between globulin or other proteins and indicator relatively much in the outer surface side (opposite side to the support, upper side) portion of the porous spreading layer.

REFERENCES:
patent: 3485587 (1969-12-01), Keston
patent: 3533749 (1977-09-01), Kleinman
patent: 3672845 (1972-06-01), Verbeck
patent: 3992158 (1976-11-01), Przybylowicz et al.
patent: 4042335 (1977-08-01), Clement
patent: 4333733 (1982-06-01), Sanford et al.

Affiliated with

Also associated with

Rating

Integral multilayer analytical element for analysis of albumin does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Integral multilayer analytical element for analysis of albumin, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Integral multilayer analytical element for analysis of albumin will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-938469