Integral multilayer analytical element

Details Integral multilayer analytical element Integral multilayer analytical element

1987-10-27

1990-01-23

Richman, Barry S.

Chemical apparatus and process disinfecting, deodorizing, preser

Analyzer, structured indicator, or manipulative laboratory...

Calorimeter

422 56, 435805, 436169, 436170, G01N 3122

Patent

active

048957046

ABSTRACT:
An integral multilayer analytical element which comprises a water-impermeable light-transmissive support, a hydrophilic layer containing a water-absorptive hydrophilic polymer binder and a spreading layer superposed in this order, and contains at least one reagent capable of reacting with a component of a sample to produce a detectable species capable of detecting by light, which is characterized in that light-scattering particulates in an amount to make light transmittance to 10 to 2.5% are contained in the above hydrophilic layer and/or a layer located on the side of the support therefrom. This element may decrease the influence of a conventional reagent layer up to the extent being negligible without lowering the sensitivity. Precision of the measurement at a low concentration range is also high, and reproducibility of the meaurement is well. Manufacture of this element is easy.

REFERENCES:
patent: 3630957 (1971-12-01), Rey et al.
patent: 3992158 (1976-11-01), Przybylowicz et al.
patent: 4042335 (1977-08-01), Clement
patent: 4312834 (1982-01-01), Vogel et al.
patent: 4587102 (1986-05-01), Nagatomo et al.

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