Insulinotropic hormone

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

514866, 530324, 530303, 530308, A61K 3724, A61K 3728, C07K 710, C07K 734

Patent

active

051207125

ABSTRACT:
A fragment of glucagon-like peptide I (GLP-1) has been found to be an insulinotropic hormone. This insulinotropic hormone comprises amino acid residues 7-37 of GLP-1. The insulinotropic hormone is useful as a potential therapy for Diabetes Mellitus.

REFERENCES:
Mojsov et al., J. Clin. Invest., vol. 79, pp. 616-619 (Feb. 1987).
Blackmore et al., FEBS Lett., 283:7-10 (1991).
Weir, G. C. et al., Diabetes, 38(3):338-342 (Mar. 1989).
Gefel, D. et al., Endocrinology, 126(4):2164-2168 (1990).
Patzelt et al., Nature, 282:260-266 (1979).
Shields et al., Nature, 289:511-514 (1981).
Lund et al., Proc. Natl. Acad. Sci. (USA), 79:345-9 (1982).
Bell et al., Nature, 302:716-718 (1983).
Lopez et al., Proc. Natl. Acad. Sci. (USA), 80:5485-5489 (1983).
Andrews et al., J. Biol. Chem., 260:3910-3914 (1985).
Heinrich et al., Endocrinol., 115:2176-2181 (1984).
Ghiglione et al., Diabetologia, 27:599-600 (1984).
Uttenthal et al., J. Clin. End. Metab., 61:472-479 (1985).
Moody et al., Nature, 289:514-516 (1981).
Yanaihara et al., FEBS Letters, 187:307-310 (1985).
Hoosein et al., FEBS Letters, 178:83-86 (1984).
Korman et al., Diabetes, 34:717-722 (1985).
Ghiglione et al., Regulatory Peptides, 13:101, Abs. (1985).
Schmidt et al., Diabetologia et al., 28:704-707 (1985).
Holst et al., FEBS, vol. 211, No. 2, pp. 169-174 (Jan. 26, 1987).
Orskov et al., Endocrinology, vol. 119, No. 4, pp. 1467-1475 (Oct. 1986).
Rudinger, Peptide Hormones. Parsons (ed.), U. Parle Press, Baltimore, pp. 1-7 (1976).
Ganong, W., Review of Medical Physiology, 9th Ed., Lange Medical Publications, Los Altos, Calif., (1976), pp. 257-276.
Drucker, D., et al., Proc. Natl. Acad. Sci. (USA), 84:3434-3438 (May 1987).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Insulinotropic hormone does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Insulinotropic hormone, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Insulinotropic hormone will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1804495

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.