Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Hormone or other secreted growth regulatory factor,...
Reexamination Certificate
2008-03-03
2010-12-14
Nickol, Gary B. (Department: 1647)
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Hormone or other secreted growth regulatory factor,...
C514S012200, C530S399000
Reexamination Certificate
active
07850976
ABSTRACT:
The invention provides an insulin resistance improving agent and a therapeutic agent for type 2 diabetes, which contain a C-terminal globular domain of adiponectin, adiponectin, or a gene for the domain or adiponectin. The invention also provides a method for improving insulin resistance and treating type 2 diabetes by administering the aforementioned agent(s).
REFERENCES:
patent: 6566332 (2003-05-01), Fruebis et al.
patent: 2006/0166873 (2006-07-01), Kadowaki et al.
patent: 96/39429 (1996-12-01), None
patent: WO/96/39429 (1996-12-01), None
Joachim Fruebis, et al., “Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice”, PNAS, vol. 98, No. 4, Feb. 13, 2001, pp. 2005-2010.
Yamauchi T. et al., The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity, Nat Med., vol. 7, No. 8, 2001, pp. 941-946.
Toshimasa Yamauchi et al., “Adiponectin ni yoru 2 Gata Tonyobyo no Insulin Teikosei no Kaizen,” Experimental Medicine, vol. 19, No. 17, 2001, pp. 2301-2305 (with Partial English Translation).
Haruhiko Osawa, et al., “2 Gata Tonyobyo Kanren Idenshi Gun no Kaimei,” Protein, Nucleic Acid and Enzyme, vol. 46, No. 16, 2001, pp. 2332-2336 (with Partial English Translation).
Kazuo Hara et al., “Seikatsu Shukanbyo no Taylor Made Iryo,” Igaku no Arumi, vol. 197, No. 13, 2001, pp. 1046-1048 (with Partial English Translation).
U.S. Appl. No. 12/041,279, filed Mar. 3, 2008, Kadowaki, et al.
U.S. Appl. No. 12/173,244, filed Jul. 15, 2008, Kadowaki, et al.
Kadowaki Takashi
Kamon Junji
Kimura Satoshi
Nagai Ryozo
Tomita Motoo
Japan Science and Technology Agency
Nickol Gary B.
Oblon, Spivak McClelland, Maier & Neustadt, L.L.P.
Stoica Elly-Gerald
LandOfFree
Insulin resistance improving agents does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Insulin resistance improving agents, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Insulin resistance improving agents will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4195652