Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – Insulin; related peptides
Reexamination Certificate
2011-01-18
2011-01-18
Lukton, David (Department: 1654)
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
Insulin; related peptides
C514S003100, C530S345000
Reexamination Certificate
active
07872095
ABSTRACT:
An insulin compound coupled to a modifying moiety having a formula:in-line-formulae description="In-line Formulae" end="lead"?—X—R1—Y-PAG-Z—R (Formula VI)in-line-formulae description="In-line Formulae" end="tail"?where,X, Y and Z are independently selected linking groups and each is optionally present, and X, when present, is coupled to the insulin compound by a covalent bond,either R1or R2is is a lower alkyl, optionally including a carbonyl group, and when R1is a lower alkyl, R2is a capping group, andPAG is a linear or branched carbon chain incorporating one or more alkalene glycol moieties, and optionally incorporating one or more additional moieties selected from the group consisting of —S—, —O—, —N—, and —C(O)—, andwhere the modifying moiety has a maximum number of 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, or 25 heavy atoms.
REFERENCES:
patent: 2626228 (1953-01-01), Petersen
patent: 2789080 (1957-04-01), Christensen
patent: 2799622 (1957-07-01), Schlichtkrull et al.
patent: 2819999 (1958-01-01), Schlichtkrull et al.
patent: 2849370 (1958-08-01), Petersen et al.
patent: 2882203 (1959-04-01), Petersen et al.
patent: 2920014 (1960-01-01), Petersen et al.
patent: 3014842 (1961-12-01), Schlichtkrull
patent: 3058885 (1962-10-01), Schlichtkrull
patent: 3060093 (1962-10-01), Poulsen et al.
patent: 3091573 (1963-05-01), Schlichtkrull
patent: 3102077 (1963-08-01), Christensen
patent: 3256153 (1966-06-01), Heimlick
patent: 3868356 (1975-02-01), Smyth
patent: 3919411 (1975-11-01), Glass et al.
patent: 3950517 (1976-04-01), Lindsay et al.
patent: 4003792 (1977-01-01), Mill et al.
patent: 4044196 (1977-08-01), Huper et al.
patent: 4087390 (1978-05-01), Shields
patent: 4093574 (1978-06-01), Shields
patent: 4100117 (1978-07-01), Shields
patent: 4179337 (1979-12-01), Davis et al.
patent: 4223163 (1980-09-01), Guilloty
patent: 4229438 (1980-10-01), Fujino et al.
patent: 4253998 (1981-03-01), Sarantakis
patent: 4277394 (1981-07-01), Fujino et al.
patent: 4338306 (1982-07-01), Kitao et al.
patent: 4348387 (1982-09-01), Brownlee et al.
patent: 4410547 (1983-10-01), Ueno et al.
patent: 4469681 (1984-09-01), Brownlee et al.
patent: 4472382 (1984-09-01), Labrie et al.
patent: 4476113 (1984-10-01), Young et al.
patent: 4554101 (1985-11-01), Hopp
patent: 4579730 (1986-04-01), Kidron et al.
patent: 4585745 (1986-04-01), Tunooka et al.
patent: 4602043 (1986-07-01), Geho
patent: 4622392 (1986-11-01), Hong et al.
patent: 4654324 (1987-03-01), Chance et al.
patent: 4662872 (1987-05-01), Cane
patent: 4684524 (1987-08-01), Eckenhoff et al.
patent: 4698264 (1987-10-01), Steinke
patent: 4704394 (1987-11-01), Geho
patent: 4717566 (1988-01-01), Eckenhoff et al.
patent: 4744976 (1988-05-01), Snipes et al.
patent: 4761287 (1988-08-01), Geho
patent: 4764592 (1988-08-01), Massey et al.
patent: 4772471 (1988-09-01), Vanlerberghe et al.
patent: 4797288 (1989-01-01), Sharma et al.
patent: 4801575 (1989-01-01), Pardridge
patent: 4822337 (1989-04-01), Newhouse et al.
patent: 4839341 (1989-06-01), Massey et al.
patent: 4840799 (1989-06-01), Appelgren et al.
patent: 4849405 (1989-07-01), Ecanow
patent: 4863896 (1989-09-01), Geho et al.
patent: 4917888 (1990-04-01), Katre et al.
patent: 4935246 (1990-06-01), Ahrens
patent: 4946828 (1990-08-01), Markussen
patent: 4957910 (1990-09-01), Sutton et al.
patent: 4963367 (1990-10-01), Ecanow
patent: 4963526 (1990-10-01), Ecanow
patent: 4994439 (1991-02-01), Longenecker et al.
patent: 5013556 (1991-05-01), Woodle et al.
patent: 5055300 (1991-10-01), Gupta
patent: 5055304 (1991-10-01), Makino et al.
patent: 5089261 (1992-02-01), Nitecki et al.
patent: 5093198 (1992-03-01), Speaker et al.
patent: 5157021 (1992-10-01), Balschmidt et al.
patent: 5162430 (1992-11-01), Rhee et al.
patent: 5164366 (1992-11-01), Balschmidt et al.
patent: 5177058 (1993-01-01), Dorschug
patent: 5202415 (1993-04-01), Jonassen et al.
patent: 5206219 (1993-04-01), Desai
patent: 5283236 (1994-02-01), Chiou
patent: 5286637 (1994-02-01), Veronese et al.
patent: 5292802 (1994-03-01), Rhee et al.
patent: 5298410 (1994-03-01), Phillips et al.
patent: 5304473 (1994-04-01), Belagaje et al.
patent: 5308889 (1994-05-01), Rhee et al.
patent: 5312808 (1994-05-01), Shorr et al.
patent: 5320094 (1994-06-01), Laube et al.
patent: 5321009 (1994-06-01), Baeder et al.
patent: 5324775 (1994-06-01), Rhee et al.
patent: 5328955 (1994-07-01), Rhee et al.
patent: 5349052 (1994-09-01), Delgado et al.
patent: 5359030 (1994-10-01), Ekwuribe
patent: 5364838 (1994-11-01), Rubsamen
patent: 5405621 (1995-04-01), Sipos
patent: 5405877 (1995-04-01), Greenwald et al.
patent: 5413791 (1995-05-01), Rhee et al.
patent: 5415872 (1995-05-01), Sipos
patent: 5420108 (1995-05-01), Shohet
patent: 5438040 (1995-08-01), Ekwuribe
patent: 5444041 (1995-08-01), Owen et al.
patent: 5446091 (1995-08-01), Rhee et al.
patent: 5457066 (1995-10-01), Frank et al.
patent: 5461031 (1995-10-01), De Felippis
patent: 5468478 (1995-11-01), Saifer et al.
patent: 5468727 (1995-11-01), Phillips et al.
patent: 5474978 (1995-12-01), Bakaysa et al.
patent: 5504188 (1996-04-01), Baker et al.
patent: 5506203 (1996-04-01), Backstrom et al.
patent: 5518998 (1996-05-01), Backstrom et al.
patent: 5523348 (1996-06-01), Rhee et al.
patent: 5529915 (1996-06-01), Phillips et al.
patent: 5534488 (1996-07-01), Hoffmann
patent: 5545618 (1996-08-01), Buckley et al.
patent: 5550188 (1996-08-01), Rhee et al.
patent: 5567422 (1996-10-01), Greenwald
patent: 5597797 (1997-01-01), Clark
patent: 5606038 (1997-02-01), Regen
patent: 5612460 (1997-03-01), Zalipsky
patent: 5631347 (1997-05-01), Baker et al.
patent: 5637749 (1997-06-01), Greenwald
patent: 5643575 (1997-07-01), Martinez et al.
patent: 5646242 (1997-07-01), Baker et al.
patent: 5650388 (1997-07-01), Shorr et al.
patent: 5650486 (1997-07-01), De Felippis
patent: 5658878 (1997-08-01), Backstrom et al.
patent: 5681567 (1997-10-01), Martinez et al.
patent: 5681811 (1997-10-01), Ekwuribe
patent: 5693609 (1997-12-01), Baker et al.
patent: 5693769 (1997-12-01), Kahne et al.
patent: 5700904 (1997-12-01), Baker et al.
patent: 5704910 (1998-01-01), Humes
patent: 5707648 (1998-01-01), Yiv
patent: 5714519 (1998-02-01), Cincotta et al.
patent: 5738846 (1998-04-01), Greenwald et al.
patent: 5747445 (1998-05-01), Backstrom et al.
patent: 5747642 (1998-05-01), De Felippis
patent: 5750497 (1998-05-01), Havelund et al.
patent: 5763396 (1998-06-01), Weiner et al.
patent: 5766620 (1998-06-01), Heiber et al.
patent: 5773581 (1998-06-01), Camble et al.
patent: 5824638 (1998-10-01), Burnside et al.
patent: 5830853 (1998-11-01), Backstrom et al.
patent: 5830918 (1998-11-01), Sportsman et al.
patent: 5843866 (1998-12-01), Parker et al.
patent: 5849860 (1998-12-01), Hakimi et al.
patent: 5853748 (1998-12-01), New
patent: 5854208 (1998-12-01), Jones et al.
patent: 5856451 (1999-01-01), Olsen et al.
patent: 5866538 (1999-02-01), Norup et al.
patent: 5866584 (1999-02-01), Cincotta et al.
patent: 5874111 (1999-02-01), Maitra et al.
patent: 5889153 (1999-03-01), Suzuki et al.
patent: 5898028 (1999-04-01), Jensen et al.
patent: 5902588 (1999-05-01), Greenwald et al.
patent: 5905140 (1999-05-01), Hansen
patent: 5907030 (1999-05-01), Shen et al.
patent: 5922675 (1999-07-01), Baker et al.
patent: 5932462 (1999-08-01), Harris et al.
patent: 5942248 (1999-08-01), Barnwell
patent: 5948751 (1999-09-01), Kimer et al.
patent: 5952008 (1999-09-01), Backstrom et al.
patent: 5952297 (1999-09-01), De Felippis et al.
patent: 5952461 (1999-09-01), Kim et al.
patent: 5955459 (1999-09-01), Bradley et al.
patent: 5962267 (1999-10-01), Shin et al.
patent: 5968549 (1999-10-01), New et al.
patent: 5969040 (1999-10-01), Hallahan et al.
patent: 5981709 (1999-11-01), Greenwald et al.
patent: 5985263 (1999-11-01), Lee et al.
patent: 5997848 (1999-12-01), Patton et al.
patent: 6004574 (1999-12-01), Backstrom et al.
patent: 6011008 (2000-01-01), Domb et al.
patent: 6025325 (2000-02-01), Campfield et al.
patent: 6034054 (2000-03-01), DeFelippis et al.
paten
Aggarwal Diti
Ekwuribe Nnochiri N.
Ferro Michelle
James Kenneth D.
Malkar Navdeep B.
Biocon Limited
Fuierer Marianne
Lukton David
Moore & Van Allen PLLC
LandOfFree
Insulin-oligomer conjugates, formulations and uses thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Insulin-oligomer conjugates, formulations and uses thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Insulin-oligomer conjugates, formulations and uses thereof will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2678760